Order Estrone (E1) Blood Test from JustLabs for $22. Price includes lab processing at Quest Diagnostics. A one-time $18 collection fee applies per order. No insurance required.

Estrone (E1) Blood Test

Estrone

Estrone (E1) is the predominant estrogen in postmenopausal women, produced mainly by fat tissue. Testing E1 is essential for evaluating hormone status after menopause and monitoring hormone replacement therapy.

Estrone (E1) is one of three naturally occurring estrogens, alongside estradiol (E2) and estriol (E3). While estradiol dominates during reproductive years, estrone becomes the primary estrogen after menopause when ovarian function declines.

After menopause, estrone is primarily produced through conversion of androstenedione (an adrenal hormone) in fat tissue. This is why postmenopausal women with higher body fat often have higher estrone levels. Estrone is a weaker estrogen than estradiol but can still have significant effects on the body.

Testing estrone is particularly valuable for postmenopausal women, especially those on hormone replacement therapy, to ensure appropriate hormone levels. It's also important for evaluating estrogen-related conditions and assessing cancer risk in postmenopausal women.

Unlike estradiol which fluctuates throughout the menstrual cycle, estrone levels are relatively stable in postmenopausal women, making it easier to interpret results.

Price

$22

Results

2-3 business days

Lab Network

Quest

Fasting

Not Required

What's Measured

Estrone

What This Test Measures

This test measures estrone (E1) concentration in pg/mL. In postmenopausal women, typical levels range from 10-60 pg/mL. Premenopausal women may have levels of 30-200 pg/mL depending on cycle phase. Men typically have levels of 10-60 pg/mL.

Who Should Consider This Test

Postmenopausal women evaluating hormone status, women on hormone replacement therapy needing monitoring, those assessing estrogen-related cancer risk, individuals with unexplained postmenopausal bleeding, and anyone requiring comprehensive hormone evaluation.

Health Insights

Conditions Screened

Menopause statusHormone imbalanceEstrogen dominanceBreast cancer risk assessmentEndometrial cancer riskOsteoporosisOvarian functionAdrenal function

Related Symptoms

Menopausal symptomsHot flashesVaginal drynessMood changesBone density concernsPostmenopausal bleedingFatigueSleep disturbances

When to Get Tested

No fasting required. Postmenopausal women can test anytime as levels are relatively stable. For premenopausal women, early follicular phase (days 2-5) provides the most consistent baseline.

Understanding Your Results

Postmenopausal women typically have estrone levels of 10-60 pg/mL. Elevated levels may indicate excess fat tissue conversion, ovarian tumors, or exogenous estrogen intake. Low levels may suggest adrenal insufficiency. Results should be interpreted with estradiol levels for a complete picture.

What to Expect

After placing your order, you'll receive an email from Rupa Health (our lab order partner) within 24 business hours to sign a consent form and schedule your blood draw at a Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 2-3 business days and will appear in your secure Justlabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

Frequently Asked Questions

$22

Typical hospital cash price: $120–$180

+ $28 in standard lab & physician fees at checkout (no additional bills later)

$18 lab collection + $10 physician order

Results in 2-3 business days

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