Order ANA Screen with Reflex to Titer and Pattern from JustLabs for $11. Price includes lab processing at Quest Diagnostics. A one-time $18 collection fee applies per order. No insurance required.

ANA Screen with Reflex to Titer and Pattern

ANA

The gold standard ANA test — screens for antinuclear antibodies and automatically provides titer level and staining pattern if positive, giving you the most complete picture in one order.

This test uses immunofluorescence assay (IFA) on human epithelial cells — the gold standard method recommended by the American College of Rheumatology for ANA testing. It combines screening and detailed analysis in one smart test.

Step 1: ANA Screen — detects antinuclear antibodies in your blood |

Step 2 (automatic if positive): Titer — measures antibody concentration (1:40, 1:80, 1:160, etc.)

Step 3 (automatic if positive): Pattern — identifies which cellular structures are targeted

This reflex approach means you only pay for detailed analysis when it's clinically relevant. If the screen is negative, you're done. If positive, you automatically get the titer and pattern that help differentiate between lupus, Sjogren's, scleroderma, and other autoimmune conditions.

Price

$11

Results

3-5 business days

Lab Network

Quest

Fasting

Not Required

What's Measured

ANA
ANA Titer
ANA Pattern

What This Test Measures

This test screens for antinuclear antibodies (ANA). If positive, it automatically measures: (1) ANA Titer — the highest dilution at which antibodies are detectable (higher numbers = more antibodies), and (2) Staining Pattern — how antibodies distribute across cell nuclei (homogeneous, speckled, nucleolar, or centromere), which helps identify specific autoimmune conditions.

Who Should Consider This Test

Anyone with symptoms suggesting autoimmune disease: unexplained joint pain, fatigue, rashes, or organ dysfunction. Also for those with family history of autoimmune conditions. This single test replaces the need to order a basic ANA screen and then follow up with titer/pattern separately.

Health Insights

Conditions Screened

Systemic lupus erythematosus (SLE)Sjogren's syndromeRheumatoid arthritisSclerodermaCREST syndromeMixed connective tissue diseasePolymyositisDermatomyositisDrug-induced lupus

Related Symptoms

Joint pain and swellingUnexplained fatigueButterfly rashRaynaud's phenomenonDry eyes and mouthMuscle weaknessHair lossSkin thickeningPhotosensitivity

When to Get Tested

No fasting required. Test when experiencing unexplained symptoms that might indicate autoimmune disease, or as part of evaluation for known autoimmune conditions.

Understanding Your Results

Negative screen: autoimmune disease is less likely (but not ruled out). Positive screen with titer: 1:160 or higher is generally clinically significant; 1:40-1:80 can occur in healthy people. Pattern interpretation: Homogeneous suggests lupus; Speckled suggests Sjogren's or lupus; Nucleolar suggests scleroderma; Centromere indicates CREST syndrome.

What to Expect

After placing your order, you'll receive an email from Rupa Health (our lab order partner) within 24 business hours to sign a consent form and schedule your blood draw at a Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 3-5 business days and will appear in your secure Justlabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

Frequently Asked Questions

$11

Typical hospital cash price: $150–$300

+ $28 in standard lab & physician fees at checkout (no additional bills later)

$18 lab collection + $10 physician order

Results in 3-5 business days

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