Order Rheumatoid Factor (RF) Blood Test from JustLabs for $8. Price includes lab processing at Quest Diagnostics. A one-time $18 collection fee applies per order. No insurance required.

Rheumatoid Factor (RF) Blood Test

RF

Rheumatoid Factor is an autoantibody commonly elevated in rheumatoid arthritis. This test helps diagnose RA and assess disease severity, though RF can also be elevated in other conditions.

Rheumatoid Factor (RF) is an autoantibody—an antibody that mistakenly attacks your own body's tissues. In rheumatoid arthritis (RA), RF targets the Fc portion of IgG antibodies, forming immune complexes that contribute to joint inflammation and damage.

RF testing is one of the key blood tests used to help diagnose rheumatoid arthritis, typically alongside anti-CCP antibodies, inflammatory markers (ESR, CRP), and clinical examination. About 70-80% of people with RA test positive for RF.

However, RF is not specific to rheumatoid arthritis. It can be elevated in other autoimmune diseases (Sjogren's syndrome, lupus), chronic infections, and even in some healthy individuals, especially older adults. A positive RF alone doesn't diagnose RA—clinical symptoms and additional testing are essential.

Price

$8

Results

2-3 business days

Lab Network

Quest

Fasting

Not Required

What's Measured

Rheumatoid Factor

What This Test Measures

This test measures the concentration of rheumatoid factor antibodies in your blood, typically reported in IU/mL. Results are often categorized as negative (<14 IU/mL), low positive (14-39 IU/mL), moderate positive (40-59 IU/mL), or high positive (≥60 IU/mL). Higher levels often correlate with more severe disease.

Who Should Consider This Test

People with joint pain, swelling, or stiffness (especially in hands and feet), those with morning stiffness lasting over an hour, individuals with symmetric joint involvement, anyone with suspected autoimmune disease, and those with a family history of rheumatoid arthritis.

Health Insights

Conditions Screened

Rheumatoid arthritisSjogren's syndromeSystemic lupus erythematosusMixed connective tissue diseaseChronic hepatitisChronic infectionsCryoglobulinemia

Related Symptoms

Joint pain and swellingMorning stiffness (>30-60 minutes)Symmetric joint involvementFatigueLow-grade feverJoint deformityNodules under the skinDry eyes or mouth

When to Get Tested

No fasting required. RF can be tested at any time. For RA diagnosis, RF is best interpreted alongside anti-CCP antibodies, ESR, and CRP, plus clinical examination by a rheumatologist.

Understanding Your Results

Negative RF (<14 IU/mL) makes RA less likely but doesn't rule it out—20-30% of RA patients are "seronegative." Positive RF suggests RA is possible, but confirmatory testing and clinical evaluation are needed. Higher RF levels often correlate with more aggressive disease, joint damage risk, and extra-articular manifestations.

What to Expect

After placing your order, you'll receive an email from Rupa Health (our lab order partner) within 24 business hours to sign a consent form and schedule your blood draw at a Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 2-3 business days and will appear in your secure Justlabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

Frequently Asked Questions

$8

Typical hospital cash price: $150–$300

+ $28 in standard lab & physician fees at checkout (no additional bills later)

$18 lab collection + $10 physician order

Results in 2-3 business days

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