Order Estradiol, Ultrasensitive (LC/MS) Blood Test from JustLabs for $29 ($47 all-in for a single-test order: $29 + one $18 lab & physician order fee per order). Price includes lab processing at Quest Diagnostics. No insurance required.
The ultrasensitive estradiol test uses advanced LC/MS technology to accurately measure very low estradiol levels that standard immunoassay tests cannot reliably detect — making it the preferred choice for men, children, and postmenopausal women.
The Estradiol, Ultrasensitive LC/MS test uses liquid chromatography with tandem mass spectrometry — the gold standard method for measuring estradiol at very low concentrations. Unlike standard immunoassay estradiol tests, this method eliminates cross-reactivity with other steroids, delivering highly accurate results even at levels below 20 pg/mL.
This test is crucial for assessing ovarian function and is used in various clinical situations including menstrual disorders, precocious or delayed puberty, and assisted reproduction protocols. For men, it is the preferred method for evaluating conditions like gynecomastia by precisely measuring estradiol levels in the low male range where standard assays lose accuracy.
Standard estradiol immunoassays can overestimate low values due to interference from other compounds in the blood. The LC/MS method avoids this problem entirely, making it indispensable for monitoring anti-estrogen therapies (such as aromatase inhibitors), assessing hormone levels in prepubertal children, and tracking postmenopausal estradiol levels where precision at low concentrations matters most.
If you need to measure estradiol in the typical female premenopausal range (30–400+ pg/mL), the standard estradiol test is sufficient and more affordable. Choose this ultrasensitive test when low-level accuracy is critical.
Price
$29
All-in
$47
incl. $18 lab & physician fee
Results
7-9 business days
Fasting
Not Required
What's Measured
What This Test Measures
This test measures estradiol (E2) concentration using LC/MS technology, which provides superior accuracy at low concentrations compared to standard immunoassay methods. Reference ranges: Males ≤29 pg/mL; Females — Follicular Phase 39–375 pg/mL, Luteal Phase 48–440 pg/mL, Postmenopausal ≤10 pg/mL.
Who Should Consider This Test
Men monitoring estradiol during testosterone replacement therapy or investigating gynecomastia, postmenopausal women tracking low estradiol levels, children being evaluated for precocious or delayed puberty, patients on aromatase inhibitor therapy, anyone needing precise measurement of low estradiol concentrations, and couples undergoing assisted reproduction protocols.
Health Insights
Conditions Screened
Related Symptoms
When to Get Tested
No fasting required. For menstruating women undergoing fertility assessment, test on days 2–5 of the menstrual cycle. For men, postmenopausal women, and children, the test can be performed at any time. If monitoring aromatase inhibitor therapy, test at consistent intervals as directed by your provider.
No fasting needed. How to prepare for your blood test →
Full guide: TRT blood work, what to test and when →
Understanding Your Results
Results are reported in pg/mL. Males should expect ≤29 pg/mL. Premenopausal females will see values that vary by cycle phase: Follicular 39–375 pg/mL, Luteal 48–440 pg/mL. Postmenopausal females typically show ≤10 pg/mL. Values outside these ranges may indicate hormonal imbalances requiring clinical evaluation. Because this test uses LC/MS, the results at low concentrations are more reliable than standard estradiol tests.
What to Expect
After placing your order, we send it straight to Quest Diagnostics — there is no consent form to sign and no partner email to wait for. Your requisition is usually ready to download from your dashboard within about an hour, and you can book your blood draw at any Quest Diagnostics location.
The blood draw typically takes just a few minutes. Results are usually available within 7-9 business days and will appear in your secure JustLabs dashboard.
Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.
How much does the Estradiol Ultrasensitive test cost?
The Estradiol Ultrasensitive test costs $29 at JustLabs — $47 all-in, since the $18 lab & physician order fee is charged once per order, however many tests you add. The price is fixed before your blood draw; no insurance or doctor visit needed.
| Option | Price | Order all-in | Notes |
|---|---|---|---|
| Estradiol Ultrasensitive at JustLabsDrawn at Quest Diagnostics | $29 | $47 | Includes the one $18 fee, charged once per order |
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Frequently Asked Questions
Hospital cash price: $120–$180
$29
+ $18 order fee · $47 all-inOne $18 fee per order covers your Quest blood draw and the independent physician order, however many tests you add.
- Results in 7-9 business days
- No fasting required
- Physician order included
No insurance needed · HSA/FSA eligible
- Physician-ordered
- CLIA-certified Quest lab
- Drawn at Quest Diagnostics
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