What Blood Tests Should I Get for Depression?

The most recommended blood tests for depression are TSH, vitamin D, vitamin B12, CBC, and testosterone (in men). Hypothyroidism is a leading medical cause of persistent low mood. These tests identify treatable conditions that mimic or worsen depression, including vitamin deficiencies and anemia.

Possible Causes

HypothyroidismVitamin D DeficiencyAnemiaLow Testosterone

Recommended Tests

TSH

$8

Measures thyroid-stimulating hormone to evaluate thyroid function. TSH is the most sensitive marker for detecting thyroi...

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Free T4

$8

Measures the unbound, active form of the thyroid hormone T4. Helps assess thyroid function and diagnose thyroid conditio...

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Vitamin D

$22

Measures vitamin D status. Deficiency is common and linked to bone health, immune function, and mood.

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B12

$8

Measures B12 levels essential for nerve function, DNA synthesis, and red blood cell formation.

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CBC w/ Diff

$5

Comprehensive blood cell analysis including red cells, white cells, platelets, and white cell differential.

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Ferritin

$9

Measures iron storage protein. Best indicator of total body iron stores.

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Testosterone

$32

Comprehensive testosterone panel measuring both free and total testosterone levels.

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When to See a Doctor

If your depression is severe, rapidly worsening, or accompanied by alarming symptoms (chest pain, shortness of breath, high fever), seek immediate medical attention. Blood tests are a valuable first step, but they don't replace evaluation by a healthcare professional.

Frequently Asked Questions

Related Symptoms

FatigueLow EnergyInsomniaBrain Fog

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Content reviewed for accuracy by the JustLabs editorial team.