Order TPO Antibodies (Thyroid Peroxidase Antibodies) Blood Test from JustLabs for $13.50 ($31.50 all-in for a single-test order: $13.50 + one $18 lab & physician order fee per order). Price includes lab processing at Quest Diagnostics. No insurance required.

TPO Antibodies (Thyroid Peroxidase Antibodies) Blood Test

TPO Ab

TPO antibodies are markers of autoimmune thyroid disease. Elevated levels indicate Hashimoto's thyroiditis, the most common cause of hypothyroidism in the United States.

Thyroid Peroxidase (TPO) is an enzyme essential for thyroid hormone production. In autoimmune thyroid disease, the immune system mistakenly produces antibodies against TPO, leading to thyroid inflammation and damage.

TPO antibodies are found in approximately 95% of Hashimoto's thyroiditis patients and 70-80% of Graves' disease patients. They can be detected years before thyroid dysfunction appears, making them useful for identifying at-risk individuals.

Hashimoto's thyroiditis causes gradual thyroid destruction, eventually leading to hypothyroidism. Early detection through TPO antibody testing allows monitoring and early intervention. Even with normal TSH, positive TPO antibodies increase the risk of future hypothyroidism.

Price

$13.50

All-in

$31.50

incl. $18 lab & physician fee

Results

2-3 business days

Fasting

Not Required

What's Measured

TPO Antibodies

What This Test Measures

This test measures the concentration of antibodies against thyroid peroxidase enzyme in your blood, typically reported in IU/mL. Results are classified as positive (elevated) or negative (normal).

Who Should Consider This Test

Anyone with symptoms of thyroid dysfunction, those with family history of autoimmune thyroid disease, people with other autoimmune conditions (increased risk), women planning pregnancy, those with unexplained fatigue or weight changes, and anyone with goiter.

Health Insights

Conditions Screened

Hashimoto's thyroiditisGraves' diseaseAutoimmune thyroid diseasePostpartum thyroiditis riskThyroiditis evaluation

Related Symptoms

FatigueWeight gainCold intoleranceHair lossDepressionConstipationDry skinMuscle achesBrain fog

When to Get Tested

No fasting required. Can be tested any time. If you have symptoms of thyroid dysfunction, test alongside TSH and Free T4 for complete evaluation.

No fasting needed. How to prepare for your blood test →

Understanding Your Results

Negative: <9 IU/mL (varies by lab). Positive: Above reference range. Positive TPO antibodies with normal TSH indicates Hashimoto's risk but not current dysfunction. The higher the antibody level, the greater the likelihood of developing hypothyroidism over time.

What to Expect

After placing your order, we send it straight to Quest Diagnostics — there is no consent form to sign and no partner email to wait for. Your requisition is usually ready to download from your dashboard within about an hour, and you can book your blood draw at any Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 2-3 business days and will appear in your secure JustLabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

How much does the TPO Ab test cost?

The TPO Ab test costs $13.50 at JustLabs — $31.50 all-in, since the $18 lab & physician order fee is charged once per order, however many tests you add. The price is fixed before your blood draw; no insurance or doctor visit needed.

OptionPriceOrder all-inNotes
TPO Ab at JustLabsDrawn at Quest Diagnostics$13.50$31.50Includes the one $18 fee, charged once per order

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Frequently Asked Questions

Thyroid1 biomarker

Hospital cash price: $120–$180

$13.50

+ $18 order fee · $31.50 all-in

  • Results in 2-3 business days
  • No fasting required
  • Physician order included

No insurance needed · HSA/FSA eligible

  • Physician-ordered
  • CLIA-certified Quest lab
  • Drawn at Quest Diagnostics

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$13.50

+ $18 order fee · $31.50 all-in