Order Vitamin B6 (Pyridoxine) Blood Test from JustLabs for $39 ($57 all-in for a single-test order: $39 + one $18 lab & physician order fee per order). Price includes lab processing at Quest Diagnostics. No insurance required.

Vitamin B6 (Pyridoxine) Blood Test

Vitamin B6

Vitamin B6 is essential for over 100 enzyme reactions, particularly protein metabolism, neurotransmitter synthesis, immune function, and hemoglobin production.

Vitamin B6 (pyridoxine) is a water-soluble vitamin that serves as a cofactor for more than 100 enzymes involved in protein metabolism, red blood cell formation, and neurotransmitter synthesis. It's essential for producing serotonin, dopamine, and GABA—brain chemicals that regulate mood, sleep, and cognitive function.

B6 also plays crucial roles in immune function, hemoglobin synthesis (oxygen-carrying protein in blood), and converting stored glycogen to glucose for energy. It works closely with B12 and folate in homocysteine metabolism, and adequate B6 helps keep homocysteine levels in check.

While deficiency is relatively uncommon in people eating varied diets, certain populations are at risk, including older adults, people with autoimmune disorders, those with kidney disease, and individuals taking certain medications. Notably, B6 toxicity from excessive supplementation can cause peripheral neuropathy—a concern that makes testing valuable for those supplementing.

Price

$39

All-in

$57

incl. $18 lab & physician fee

Results

3-5 business days

Fasting

Not Required

What's Measured

Vitamin B6

What This Test Measures

This test measures pyridoxal 5'-phosphate (PLP), the active form of vitamin B6, in your blood plasma. Normal levels typically range from 5-50 ng/mL. Levels below 5 ng/mL indicate deficiency, while chronically elevated levels from supplementation may cause toxicity.

Who Should Consider This Test

People with peripheral neuropathy symptoms, those taking high-dose B6 supplements (for nausea, PMS, carpal tunnel), individuals with autoimmune conditions (especially rheumatoid arthritis), people with kidney disease, older adults with poor nutrition, anyone with anemia not responding to iron, and those on medications that deplete B6.

Health Insights

Conditions Screened

B6 deficiencyB6 toxicity (from over-supplementation)Anemia evaluationPeripheral neuropathy workupHomocysteine metabolism assessmentMedication-induced deficiency

Related Symptoms

Peripheral neuropathy (numbness, tingling)Confusion or difficulty concentratingDepression or irritabilityWeakened immune functionCracked, sore lips (cheilosis)Swollen, sore tongueSkin rashesAnemia symptoms (fatigue, weakness)

When to Get Tested

No fasting required. B6 supplements should be stopped for 24-48 hours before testing for accurate baseline results. Inform your provider about all supplements you take.

No fasting needed. How to prepare for your blood test →

Understanding Your Results

Normal B6 (PLP) is 5-50 ng/mL. Low levels indicate deficiency requiring supplementation and investigation of causes. Very low levels can cause anemia and neurological symptoms. High levels (>100 ng/mL) from chronic supplementation above 100mg/day can paradoxically cause sensory neuropathy.

What to Expect

After placing your order, we send it straight to Quest Diagnostics — there is no consent form to sign and no partner email to wait for. Your requisition is usually ready to download from your dashboard within about an hour, and you can book your blood draw at any Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 3-5 business days and will appear in your secure JustLabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

How much does the Vitamin B6 test cost?

The Vitamin B6 test costs $39 at JustLabs — $57 all-in, since the $18 lab & physician order fee is charged once per order, however many tests you add. The price is fixed before your blood draw; no insurance or doctor visit needed.

OptionPriceOrder all-inNotes
Vitamin B6 at JustLabsDrawn at Quest Diagnostics$39$57Includes the one $18 fee, charged once per order

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Frequently Asked Questions

Vitamins & Minerals1 biomarker

Hospital cash price: $100–$200

$39

+ $18 order fee · $57 all-in

  • Results in 3-5 business days
  • No fasting required
  • Physician order included

No insurance needed · HSA/FSA eligible

  • Physician-ordered
  • CLIA-certified Quest lab
  • Drawn at Quest Diagnostics

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