STI Test Panel: HIV, Hepatitis B & C, Syphilis, Chlamydia & Gonorrhea

Five Quest tests on one blood sample and one urine sample: HIV-1/2 antigen and antibody, 4th generation (with automatic antibody differentiation and, if needed, HIV-1 RNA); hepatitis B surface antigen (with automatic confirmation); hepatitis C antibody (with automatic HCV RNA if reactive or borderline); syphilis RPR (with automatic titer and Treponema pallidum antibody confirmation if reactive); and chlamydia and gonorrhea RNA by TMA (NAAT) on first-catch urine. All of those follow-up tests are included in the price.

Anyone who wants a broad check: after a new partner or a partner who tested positive, before stopping condom use with a partner, if you have had more than one partner since your last test, or simply if you have never been tested. CDC screening guidance includes: HIV at least once for everyone 13-64 and at least yearly with ongoing risk; hepatitis B and hepatitis C at least once for every adult; yearly chlamydia and gonorrhea for sexually active women under 25 and older women at increased risk; and for sexually active gay and bisexual men, at least yearly HIV, syphilis, chlamydia and gonorrhea, every 3-6 months at increased risk. You do not need to share a reason to test.

For routine screening, any time; no fasting is needed. After a specific possible exposure, timing matters, because each infection becomes detectable on a different schedule. HIV: this lab antigen/antibody test usually detects HIV 18 to 45 days after exposure. Chlamydia and gonorrhea: test when you have a new partner or a partner tests positive, and retest about 3 months after any treatment. Syphilis: the first sore usually appears about 3 weeks after exposure, and blood tests can still be negative at that point. Hepatitis B: surface antigen can appear as early as 1-2 weeks but sometimes not until 11-12 weeks. Hepatitis C: antibodies usually take 8-11 weeks to appear. A negative result inside these windows is not conclusive, so plan to retest after the longest window that applies to you. If the exposure was in the last 72 hours, contact a clinician or urgent care now about HIV post-exposure prophylaxis (PEP) instead of waiting to test. If you have symptoms such as a sore, discharge or burning, see a clinician promptly.

Each infection is reported separately. Non-reactive or not detected means no sign of that infection at the time of the test; if you tested inside a window period, retest later. HIV: a reactive screen is automatically checked with an antibody differentiation test and, if needed, HIV RNA; the final interpretation says whether HIV is confirmed. Hepatitis B: a reactive surface antigen is automatically confirmed; a confirmed result means the virus is present now. Hepatitis C: a reactive antibody triggers an RNA test; RNA detected means current infection, RNA not detected usually means a past infection that cleared. Syphilis: a reactive RPR is titered and confirmed with a treponemal test; a positive treponemal test usually stays positive for life even after treatment, so a clinician reads both results together with your history. Chlamydia or gonorrhea detected means a current urogenital infection. Chlamydia, gonorrhea and syphilis are curable with antibiotics, hepatitis C is curable with oral medication, and HIV and hepatitis B are treatable with ongoing care. JustLabs results are informational; review any positive or unclear result with a clinician promptly.