Order Syphilis Screen (RPR) Blood Test from JustLabs for $6. Price includes lab processing at Quest Diagnostics. A one-time $18 collection fee applies per order. No insurance required.
The RPR (Rapid Plasma Reagin) test is a screening blood test for syphilis. This sexually transmitted infection is curable when caught early but can cause serious health problems if left untreated.
Syphilis is a sexually transmitted infection (STI) caused by the bacterium Treponema pallidum. It progresses through stages (primary, secondary, latent, tertiary) and can cause serious complications if untreated, including damage to the heart, brain, and other organs.
The RPR (Rapid Plasma Reagin) test detects antibodies that your body produces in response to cellular damage caused by the syphilis bacteria. It's a nontreponemal test, meaning it doesn't detect the bacteria directly but rather your body's reaction to infection.
Key points about syphilis and RPR testing:
- Syphilis is highly treatable with antibiotics when caught early
- The infection can be silent (no symptoms) for years
- Pregnant women are routinely screened because syphilis can be passed to babies
- If RPR is positive, a confirmatory treponemal test is required
- RPR can also be used to monitor treatment response (titers decrease with successful treatment)
Price
$6
Results
1 business days
Lab Network
Quest
Fasting
Not Required
What's Measured
What This Test Measures
This test detects reagin antibodies in your blood that are produced in response to syphilis infection. Results are reported as reactive (positive) or nonreactive (negative). Reactive results include a titer (1:1, 1:2, 1:4, etc.) indicating antibody concentration.
Who Should Consider This Test
Anyone who is sexually active and has not been recently tested, people with new sexual partners, those with symptoms of syphilis (sores, rash, flu-like symptoms), pregnant women, individuals with other STIs (co-infection is common), and anyone exposed to someone with syphilis.
Health Insights
Conditions Screened
Related Symptoms
When to Get Tested
No fasting required. Test 3-6 weeks after potential exposure (this is the window period before antibodies develop). If initial test is negative but exposure is suspected, repeat in 3 months. Pregnant women should be tested at first prenatal visit.
Understanding Your Results
Nonreactive (negative) = No current infection detected. Reactive (positive) = Requires confirmatory testing. A reactive RPR can indicate current infection, past treated infection, or rarely a false positive. Titer levels help distinguish active infection from past exposure and monitor treatment.
What to Expect
After placing your order, you'll receive an email from Rupa Health (our lab order partner) within 24 business hours to sign a consent form and schedule your blood draw at a Quest Diagnostics location.
The blood draw typically takes just a few minutes. Results are usually available within 1 business days and will appear in your secure Justlabs dashboard.
Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.
Frequently Asked Questions
$6
Typical hospital cash price: $100–$200
+ $28 in standard lab & physician fees at checkout (no additional bills later)
$18 lab collection + $10 physician order
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