Order Alkaline Phosphatase (ALP) Blood Test from JustLabs for $5 ($23 all-in for a single-test order: $5 + one $18 lab & physician order fee per order). Price includes lab processing at Quest Diagnostics. No insurance required.

Alkaline Phosphatase (ALP) Blood Test

ALP

Alkaline phosphatase (ALP) is an enzyme made mainly in the liver, bile ducts and bones. A high level can point to a bile-flow problem in the liver or to increased bone activity, so it is usually read alongside other liver tests.

Alkaline phosphatase (ALP) is an enzyme found throughout the body, with the highest amounts in the liver, the bile ducts and bone. Each tissue makes its own form, and they all add up to the single ALP number on your report.

ALP rises when bile flow is slowed or blocked (cholestasis) and when bone-building cells are especially active. That is why children and teenagers, whose bones are growing, normally have much higher ALP than adults, and why ALP rises in late pregnancy. In adults, a high ALP is usually followed by other tests to find out whether it comes from the liver or the bone.

ALP is already part of the Comprehensive Metabolic Panel (CMP) and the Hepatic Function Panel on JustLabs. Ordering it on its own makes sense when you are tracking this one value: re-checking an ALP that was high last time, or monitoring it as your clinician advised. Adding GGT to the same order is a common way to help tell a liver source from a bone source: GGT tends to rise with ALP when the liver is involved but not with bone conditions.

ALP on its own cannot say what is wrong. A clinician interprets it with your other liver tests, calcium, vitamin D, age and history.

Price

$5

All-in

$23

incl. $18 lab & physician fee

Results

1-3 business days

Fasting

Not Required

What's Measured

Alkaline Phosphatase (ALP)

What This Test Measures

This test measures alkaline phosphatase activity in your blood serum. Quest notes that ALP is used in the diagnosis of liver and bile-duct (hepatobiliary) disorders and of bone disease with increased bone-forming (osteoblastic) activity. The test reports total ALP; it does not separate the liver and bone forms.

Who Should Consider This Test

People re-checking an ALP that came back high or low; people whose clinician wants ALP followed over time for a known liver or bone condition; and people being evaluated for liver or bone problems, alongside other tests. If you have symptoms such as jaundice, itching, bone pain or unexplained fractures, see a clinician; a full liver panel is usually the better first test.

Health Insights

Conditions Screened

Bile duct obstruction (cholestasis)Liver diseasePaget disease of boneBone disorders with high bone turnoverHypophosphatasia (low ALP)

Related Symptoms

Jaundice (yellow skin or eyes)Persistent itchingDark urine or pale stoolsAbdominal painBone painFractures with little traumaFatigue

When to Get Tested

Any time of day; no fasting is required. Because a fatty meal can cause a small rise in ALP, testing before eating or after a light meal gives the most comparable results when you are re-checking a value.

No fasting needed. How to prepare for your blood test →

Understanding Your Results

A result within the lab's reference range is reassuring for this marker. A high ALP from the liver can reflect blocked bile ducts, cirrhosis, hepatitis or mononucleosis; a high ALP with otherwise normal liver tests can point to a bone condition such as Paget disease of bone. Moderate rises are also seen with heart failure, some infections and Hodgkin lymphoma, and ALP is normally higher in children, teenagers and late pregnancy. A low ALP is less common and can be linked to zinc or protein deficiency, malnutrition, thyroid disease, pernicious anemia, Wilson disease or, rarely, the inherited condition hypophosphatasia. Next steps after an abnormal result usually include other liver tests, GGT or an ALP isoenzyme test, chosen by a clinician. JustLabs results are informational; review them with a clinician.

What to Expect

After placing your order, we send it straight to Quest Diagnostics — there is no consent form to sign and no partner email to wait for. Your requisition is usually ready to download from your dashboard within about an hour, and you can book your blood draw at any Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 1-3 business days and will appear in your secure JustLabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

How much does the ALP test cost?

The ALP test costs $5 at JustLabs — $23 all-in, since the $18 lab & physician order fee is charged once per order, however many tests you add. The price is fixed before your blood draw; no insurance or doctor visit needed.

OptionPriceOrder all-inNotes
ALP at JustLabsDrawn at Quest Diagnostics$5$23Includes the one $18 fee, charged once per order

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Frequently Asked Questions

Liver1 biomarker

Hospital cash price: $120–$200

$5

+ $18 order fee · $23 all-in

  • Results in 1-3 business days
  • No fasting required
  • Physician order included

No insurance needed · HSA/FSA eligible

  • Physician-ordered
  • CLIA-certified Quest lab
  • Drawn at Quest Diagnostics

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