Order ApoE Genotype (Apolipoprotein E Genetic) Test from JustLabs for $113 ($131 all-in for a single-test order: $113 + one $18 lab & physician order fee per order). Price includes lab processing at Quest Diagnostics. No insurance required.

ApoE Genotype (Apolipoprotein E Genetic) Test

ApoE Gene

The ApoE genotype test identifies which variants of the ApoE gene you carry, providing insight into your genetic risk for heart disease and Alzheimer's.

Apolipoprotein E (ApoE) is a protein crucial for cholesterol transport and brain health. There are three common variants: E2, E3, and E4. Everyone inherits two copies (one from each parent), creating genotypes like E3/E3 (most common), E3/E4, or E4/E4.

The E4 variant is associated with higher LDL cholesterol, increased cardiovascular risk, and significantly elevated Alzheimer's risk. The E2 variant may offer some protection against heart disease but is associated with a rare lipid disorder. This one-time genetic test provides lifelong information about your genetic predisposition.

Price

$113

All-in

$131

incl. $18 lab & physician fee

Results

5-7 business days

Fasting

Not Required

What's Measured

ApoE Genotype

What This Test Measures

This genetic test identifies your ApoE genotype - which two ApoE alleles (E2, E3, or E4) you carry. Results are permanent and never change. About 25% of people carry at least one E4 allele.

Who Should Consider This Test

Anyone wanting to understand their genetic risk for cardiovascular disease or Alzheimer's. Particularly valuable for those with family history of early heart disease or dementia, people with high LDL despite lifestyle changes, or those who want personalized prevention strategies.

Health Insights

Conditions Screened

Cardiovascular disease riskAlzheimer's disease riskHyperlipidemiaResponse to statin therapyType III hyperlipoproteinemia (E2/E2)

Related Symptoms

Family history of heart diseaseFamily history of Alzheimer'sHigh cholesterol not responding to treatmentProactive health planningPersonalized medicine interest

When to Get Tested

No fasting required. This is a one-time test - your genotype never changes. Consider testing if you want genetic insight into your cardiovascular and cognitive health risks.

No fasting needed. How to prepare for your blood test →

Understanding Your Results

E3/E3 (most common): average risk. E3/E4 or E4/E4: increased cardiovascular and Alzheimer's risk - more aggressive prevention recommended. E2/E3: may have lower cardiovascular risk. E2/E2: rare, associated with Type III hyperlipoproteinemia. Having E4 doesn't mean you'll develop disease, and not having it doesn't guarantee you won't.

What to Expect

After placing your order, we send it straight to Quest Diagnostics — there is no consent form to sign and no partner email to wait for. Your requisition is usually ready to download from your dashboard within about an hour, and you can book your blood draw at any Quest Diagnostics location.

The blood draw typically takes just a few minutes. Results are usually available within 5-7 business days and will appear in your secure JustLabs dashboard.

Our results include reference ranges and easy-to-understand indicators showing whether your values are within normal limits.

How much does the ApoE Gene test cost?

The ApoE Gene test costs $113 at JustLabs — $131 all-in, since the $18 lab & physician order fee is charged once per order, however many tests you add. The price is fixed before your blood draw; no insurance or doctor visit needed.

OptionPriceOrder all-inNotes
ApoE Gene at JustLabsDrawn at Quest Diagnostics$113$131Includes the one $18 fee, charged once per order

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Frequently Asked Questions

Heart Health1 biomarker

Hospital cash price: $200–$400

$113

+ $18 order fee · $131 all-in

  • Results in 5-7 business days
  • No fasting required
  • Physician order included

No insurance needed · HSA/FSA eligible

  • Physician-ordered
  • CLIA-certified Quest lab
  • Drawn at Quest Diagnostics

Need Help Choosing?

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